Objective: This study aimed to determine the most common musculoskeletal disorders among ophthalmologists in the Kingdom of Saudi Arabia. Methods: Ophthalmologists throughout the Kingdom were contacted by mail or by person. After obtaining their informed consent, we requested them to fill the Health Status Questionnaire. Results: Out of the 330 ophthalmologists contacted, 150 of them responded, but 43 provided insufficient data and 15 were practicing abroad and they were excluded. The remaining 92 surveys were analyzed for this study. Most of the ophthalmologists complained of low back pain (48%) and neck pain (40%). Other common areas of pain reported were that of the shoulders (27%), mid back (23%), upper back (16%), knee (16%), and gluteal region (15%). Conclusion: The common musculoskeletal disorders among ophthalmologists were found to be low back pain and neck pain. Most of the ophthalmologists believed that abnormal posture during surgery and lack of exercise are the most common reasons for their pain. Many of them reported that pain affected both their professional and personal lives.